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  Indian J Med Microbiol
 

Figure 1: Hepatocytes of untreated (a and c) and dimethyl dimethoxy biphenyl dicarboxylate-treated (b and d) mice for 1 and 3 months, respectively (IHC, DAB, ×400), showing large number of positive cytochrome P450 (a and c) with marked intensity (brownish cytoplasmic stain) and binucleated nuclei (red arrows), and mild-moderate number of positive cytochrome P450 (b and d) with binucleated nuclei (red arrow)

Figure 1: Hepatocytes of untreated (a and c) and dimethyl dimethoxy biphenyl dicarboxylate-treated (b and d) mice for 1 and 3 months, respectively (IHC, DAB, ×400), showing large number of positive cytochrome P450 (a and c) with marked intensity (brownish cytoplasmic stain) and binucleated nuclei (red arrows), and mild-moderate number of positive cytochrome P450 (b and d) with binucleated nuclei (red arrow)