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  Indian J Med Microbiol
 

Figure 1: Schematic model of novel inhibitors in Fas-associated death domain-Procaspase 8 interaction and Caspase 3 activation via Caspase 8. Diagram shows a cell membrane bound death receptor tumor necrosis factor receptor activated by the binding of the ligand initiate the intrinsic apoptosis pathway. Activation of the pathway leads to the formation of death-inducing signaling complex, which initiate a cascade through Caspase 8

Figure 1: Schematic model of novel inhibitors in Fas-associated death domain-Procaspase 8 interaction and Caspase 3 activation via Caspase 8. Diagram shows a cell membrane bound death receptor tumor necrosis factor receptor activated by the binding of the ligand initiate the intrinsic apoptosis pathway. Activation of the pathway leads to the formation of death-inducing signaling complex, which initiate a cascade through Caspase 8