Journal of Advanced Pharmaceutical Technology & Research

ORIGINAL ARTICLE
Year
: 2011  |  Volume : 2  |  Issue : 2  |  Page : 104--109

Antibacterial and antifungal activities from leaf extracts of Cassia fistula l.: An ethnomedicinal plant


Nayan R Bhalodia, VJ Shukla 
 Department of Pharmaceutical, I.P.G.T and R.A, Gujarat Ayurved University, Jamnagar, Gujarat, India

Correspondence Address:
Nayan R Bhalodia
Panchavati Gaushala, 95-B, Sarusection Road, Opp. Gita Bunglow, Jamnagar - 361 008, Gujarat
India

This study was carried out with an objective to investigate the antibacterial and antifungal potentials of leaves of Cassia fistula Linn. The aim of the study is to assess the antimicrobial activity and to determine the zone of inhibition of extracts on some bacterial and fungal strains. In the present study, the microbial activity of hydroalcohol extracts of leaves of Cassia fistula Linn. (an ethnomedicinal plant) was evaluated for potential antimicrobial activity against medically important bacterial and fungal strains. The antimicrobial activity was determined in the extracts using agar disc diffusion method. The antibacterial and antifungal activities of extracts (5, 25, 50, 100, 250 ΅g/ml) of Cassia fistula were tested against two Gram-positive--Staphylococcus aureus, Streptococcus pyogenes; two Gram-negative--Escherichia coli, Pseudomonas aeruginosa human pathogenic bacteria; and three fungal strains--Aspergillus niger, Aspergillus clavatus, Candida albicans. Zone of inhibition of extracts were compared with that of different standards like ampicillin, ciprofloxacin, norfloxacin, and chloramphenicol for antibacterial activity and nystatin and griseofulvin for antifungal activity. The results showed that the remarkable inhibition of the bacterial growth was shown against the tested organisms. The phytochemical analyses of the plants were carried out. The microbial activity of the Cassia fistula was due to the presence of various secondary metabolites. Hence, these plants can be used to discover bioactive natural products that may serve as leads in the development of new pharmaceuticals research activities.


How to cite this article:
Bhalodia NR, Shukla V J. Antibacterial and antifungal activities from leaf extracts of Cassia fistula l.: An ethnomedicinal plant.J Adv Pharm Technol Res 2011;2:104-109


How to cite this URL:
Bhalodia NR, Shukla V J. Antibacterial and antifungal activities from leaf extracts of Cassia fistula l.: An ethnomedicinal plant. J Adv Pharm Technol Res [serial online] 2011 [cited 2021 May 8 ];2:104-109
Available from: https://www.japtr.org/article.asp?issn=2231-4040;year=2011;volume=2;issue=2;spage=104;epage=109;aulast=Bhalodia;type=0