Journal of Advanced Pharmaceutical Technology & Research

REVIEW ARTICLE
Year
: 2010  |  Volume : 1  |  Issue : 4  |  Page : 381--387

Mucoadhesive drug delivery system: An overview


Bindu M Boddupalli1, Zulkar N.K Mohammed1, Ravinder A Nath2, David Banji1 
1 Department of Pharmaceutics, Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh - 508 001, India
2 Faculty of Technology, Osmania University, Hyderabad, Andhra Pradesh - 500 013, India

Correspondence Address:
Bindu M Boddupalli
Department of Pharmaceutics, Nalanda College of Pharmacy, Cherlapalli, Nalgonda, Andhra Pradesh - 508 001
India

Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT. Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic activity. In this regard, this review covers the areas of mechanisms and theories of mucoadhesion, factors influencing the mucoadhesive devices and also various mucoadhesive dosage forms.


How to cite this article:
Boddupalli BM, Mohammed ZN, Nath RA, Banji D. Mucoadhesive drug delivery system: An overview.J Adv Pharm Technol Res 2010;1:381-387


How to cite this URL:
Boddupalli BM, Mohammed ZN, Nath RA, Banji D. Mucoadhesive drug delivery system: An overview. J Adv Pharm Technol Res [serial online] 2010 [cited 2020 Nov 24 ];1:381-387
Available from: https://www.japtr.org/article.asp?issn=2231-4040;year=2010;volume=1;issue=4;spage=381;epage=387;aulast=Boddupalli;type=0