Journal of Advanced Pharmaceutical Technology & Research

ORIGINAL ARTICLE
Year
: 2010  |  Volume : 1  |  Issue : 1  |  Page : 83--87

Preliminary investigation on antipyretic activity of Cuscuta Reflexa in rats


Sanjib Bhattacharya, Bodhisattva Roy 
 Bengal School of Technology (A College of Pharmacy), Sugandha, Hooghly, West Bengal, India

Correspondence Address:
Sanjib Bhattacharya
Bengal School of Technology (A College of Pharmacy), Sugandha, Hooghly, West Bengal
India

In present study, the antipyretic activity of aqueous and ethanol extracts from Cuscuta reflexa Roxb. (Cuscutaceae) was evaluated using Brewer«SQ»s yeast induced pyrexia in rats. Both the extracts at 200 and 400 mg/kg body weight dose significantly (p < 0.05) reduced the increased rectal temperature. The extracts started reducing the elevated rectal temperature after 3 h of treatment in a dose related manner. At the dose of 400 mg/kg body weight the aqueous and ethanol extract reduced 79 % and 83.8 % respectively of the elevated rectal temperature as compared to reference drug paracetamol (96.5 %) after 6 h of treatment. It was therefore concluded that both the extracts of C. reflexa demonstrated antipyretic activity, the ethanol extract was found to be slightly potent than the aqueous extract.


How to cite this article:
Bhattacharya S, Roy B. Preliminary investigation on antipyretic activity of Cuscuta Reflexa in rats.J Adv Pharm Technol Res 2010;1:83-87


How to cite this URL:
Bhattacharya S, Roy B. Preliminary investigation on antipyretic activity of Cuscuta Reflexa in rats. J Adv Pharm Technol Res [serial online] 2010 [cited 2021 Oct 20 ];1:83-87
Available from: https://www.japtr.org/article.asp?issn=2231-4040;year=2010;volume=1;issue=1;spage=83;epage=87;aulast=Bhattacharya;type=0