| REVIEW ARTICLE |
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| Year : 2010 | Volume
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| Issue : 4 | Page : 381-387 |
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Mucoadhesive drug delivery system: An overview
Bindu M Boddupalli1, Zulkar N.K Mohammed1, Ravinder A Nath2, David Banji1
1 Department of Pharmaceutics, Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh - 508 001, India
2 Faculty of Technology, Osmania University, Hyderabad, Andhra Pradesh - 500 013, India
Correspondence Address:
Bindu M Boddupalli
Department of Pharmaceutics, Nalanda College of Pharmacy, Cherlapalli, Nalgonda, Andhra Pradesh - 508 001
India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0110-5558.76436
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Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT. Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic activity. In this regard, this review covers the areas of mechanisms and theories of mucoadhesion, factors influencing the mucoadhesive devices and also various mucoadhesive dosage forms. |
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