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ORIGINAL ARTICLE
Year : 2019  |  Volume : 10  |  Issue : 4  |  Page : 190-194

Antimicrobial activity of a novel polyherbal combination for the treatment of vaginal infection


1 Department of Pharmacognosy, B. S. Anangpuria Institute of Pharmacy, Faridabad, Haryana, India
2 Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi, India
3 Department of Pharmaceutics, NIET Pharmacy Institute, Greater Noida, Uttar Pradesh, India

Correspondence Address:
Gaurav K Jain
Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/japtr.JAPTR_3_19

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The present study evaluated the antimicrobial activity of Azadirachta indica (AI), Cichorium intybus (CI), and Trigonella foenum-graecum (TFG) against bacterial and fungal pathogens responsible for the vaginal infections. The AI, CI, and TFG were selected to include antimicrobial and antifungal action against wide range of microbes. The different extracts of the herbs were evaluated for antibacterial and antifungal activity by well diffusion assays. Based on the results, the combination was selected and evaluated, “polyherbal antimicrobial (PHA).” The developed PHA extract demonstrated synergistic broad-spectrum antimicrobial activities including antibacterial and antifungal activity (minimum inhibition concentration: 5–7 mg/ml).


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