Home  |  About JAPTR |  Editorial board  |  Search |  Ahead of print  |  Current issue  |  Archives |  Submit article  |  Instructions  |  Subscribe  |  Advertise  |  Contacts  |Login 
Users Online: 373   Home Print this page Email this page Small font sizeDefault font sizeIncrease font size
     
ORIGINAL ARTICLE
Year : 2016  |  Volume : 7  |  Issue : 3  |  Page : 87-90

Effects of Cr3+ ions on electrophysiological parameters of isolated skin of toad Pleurodema thaul


1 Department of Clinical Biochemistry and Immunohematology, Faculty of Health Sciences, University of Talca, Talca, Chile
2 Institute of Chemistry and Natural Resources, University of Talca, Talca, Chile

Correspondence Address:
Ricardo I Castro Cepeda
Institute of Chemistry and Natural Resources, Universidad de Talca, Talca
Chile
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-4040.184587

Rights and Permissions

In view of the toxicity of chromium (Cr3+) ions, it was explored the damaging effects that this ion could induce in cell membranes. The measurement of the effects induced by Cr3+ ions on electrophysiological parameters of short-circuit current and on the potential difference were investigated using the outer side (mucosal) and the inner side (serosal) of toad Pleurodema thaul skin. The results showed a decreased on electrophysiological parameters when it were administered concentrations of 33, 100 and 200 μM of Cr3+, the results also suggest that the administration of Cr3+ inhibits the ion transport in toad skin by the interaction of Cr3+ with lipid bilayers or protein constituents of membrane, and not by an inhibition of the active transport of ions across Na+ channels.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed1852    
    Printed22    
    Emailed0    
    PDF Downloaded195    
    Comments [Add]    

Recommend this journal