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ORIGINAL ARTICLE
Year : 2011  |  Volume : 2  |  Issue : 3  |  Page : 177-183

Synergistic antioxidant activity of green tea with some herbs


1 Department of Pharmacognosy, NMT Gujarati College of Pharmacy, Indore, Madhya Pradesh, India
2 Department of Pharmacognosy,Babaria Institute of Pharmacy, Vadodara, Gujarat, India
3 Department of Pharmacognosy,S.K. Patel College of Pharmaceutical Education and Research, Ganpat University, Mehsana, India

Correspondence Address:
Dheeraj P Jain
Department of Pharmacognosy, NMT Gujarati College of Pharmacy, Scheme No. 54, A.B. Road, Near Bombay Hospital, Indore - 452 010, Madhya Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2231-4040.85538

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Cardiovascular diseases, cancer, arthritis, etc. are caused by free radicals that are byproducts of metabolic pathways. Selected plants namely Vitis vinifera, Phyllanthus emblica L., Punica granatum, Cinnamomum cassia, Ginkgo biloba L., and Camellia sinensis Linn. are reported to produce antioxidant property. This study is undertaken to support the hypothesis that formulation of a polyherbal combination of these plants shows a synergistic effect with green tea. The extracts of each drug were characterized by phytochemical studies and tests for phenolics and flavonoids. In vitro antioxidant activity for individual drug and its combination was determined by 1,1-diphenyl-2-picrylhydrazyl (DPPH), superoxide, and nitric oxide free radical scavenging methods. Our results suggest that a combination of all these herbs with green tea can synergistically enhance antioxidant activity and thus lower doses of each herb with green tea may be used. Antioxidant potential of polyherbal combination was also comparable to that of standard ascorbic acid. Studies showed that selected individual plants contained abundant quantity of phenolics and flavonoids and their polyherbal combination with green tea was found to produce best antioxidant activity among all individual extracts. This will help in avoiding undesirable side effects due to higher doses of single herb.


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