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ORIGINAL ARTICLE
Year : 2010  |  Volume : 1  |  Issue : 1  |  Page : 88-96

Design and evaluation of a metronidazole central core matrix tablet


1 Acharya & B.M. Reddy College of Pharmacy, Bangalore, India
2 BBDNITM, Akhilesh Das Nagar, Sector-1, Faizabad Road, Lucknow, India
3 G.R. Medical College, Gwalior, India
4 Malla Reddy College of Pharmacy, Hyderabad, India

Correspondence Address:
Upendra Nagaich
Acharya & B.M. Reddy College of Pharmacy, Bangalore
India
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Source of Support: None, Conflict of Interest: None


PMID: 22247836

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In this paper, a study of different concentration of HPMC K 15 M exerts influence on the drug release process from a new controlled drug delivery system has been realized in order to obtain a constant release rate during a prolonged period of time, for a programmed drug release. The drug release profiles obtained for the different batches have shown an interesting relationship between the particle size of the channeling agent used and the length of different operational periods.


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